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Article

A novel multi-omics mendelian randomization method for gene set enrichment and its application to psychiatric disorders

2024-04-15

Abstract excerpt

Genome-wide association studies (GWAS) of psychiatric disorders (PD) yield numerous loci with significant signals, but often do not implicate specific genes. Because GWAS risk loci are enriched in expression/protein/methylation quantitative loci (e/p/mQTL, hereafter xQTL), transcriptome/proteome/methylome-wide association studies (T/P/MWAS, hereafter XWAS) that integrate xQTL and GWAS information, can link GWAS si...

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Literature Corpus work
9b53bd33-b861-595e-b1fe-09cc2ba3097e
DOI
10.1101/2024.04.14.24305811
Open publication

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A novel multi-omics mendelian randomization method for gene set enrichment and its application to psychiatric disordersDOI 10.1101/2024.04.14.24305811
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