Article

A Framework to Analyse and Interpret Mouse Functional Genome by Prioritizing High Impact SNPs

2020-12-19

Abstract excerpt

The essential understanding of disease pathogenesis and enabling genetic findings to be used for developing new therapeutics, is missing in the identifications of genomic loci through whole genome association studies (GWAS). Here we describe a new computational method (mMap) that reduces this gap by characterizing the functional and regulatory impact of allelic variation. The method incorporates the precomputed an...

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Literature Corpus work: 36b981fc-82f6-57ca-a38f-2507e57f47ad
DOI: 10.1101/2020.12.18.423378

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