Article

Annotation Regression for Genome-Wide Association Studies with an Application to Psychiatric Genomic Consortium Data

2016-04-25

Abstract excerpt

Although genome-wide association studies (GWAS) have been successful at finding thousands of disease-associated genetic variants (GVs), identifying causal variants and elucidating the mechanisms by which genotypes influence phenotypes are critical open questions. A key challenge is that a large percentage of disease-associated GVs are potential regulatory variants located in noncoding regions, making them difficul...

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Literature Corpus work: 06c35c8a-e4ab-59aa-bd22-244caecffccb
DOI: 10.1101/049932

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