Article
Searching joint association signals in CATIE schizophrenia genome-wide association studies through a refined integrative network approach.
BMC genomics - 1 Jan 2012
Jia Peilin, Zhao Zhongming
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) have generated a wealth of valuable genotyping data for complex diseases/traits. A large proportion of these data are embedded with many weakly associated markers that have been missed in traditional single marker analyses, but they may provide valuable insights in dissecting the genetic components of diseases. Gene set analysis (GSA) augmented by protein-protein...
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