Article
Copy Number Variation and Frequency of rs179008 in TLR7 Gene Associated with Systemic Lupus Erythematosus in Two Mexican Populations.
Journal of immunology research - 1 Jan 2022
Pacheco Guillermo Valencia, Nakazawa Ueji Yumi E, Bello Julián Ramírez, Barbosa Cobos Rosa E, Jiménez Becerra Eduardo D, González Herrera Lizbeth J, Pérez Mendoza Gerardo J, Rivero Cárdenas Nubia A, Angulo Ramírez Angélica V, López Villanueva Ricardo F
Abstract excerpt
Systemic Lupus Erythematosus (SLE) is an autoimmune disease in which genetic factors play a role in the susceptibility to develop it. Genes related to the synthesis of interferons such as TLR7 and genetics factors such as single nucleotide polymorphisms (SNPs) or copies number variation (CNV) in the gene have been involved with the development of the disease. The genetic differences between the populations...
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