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Article

Single nucleotide polymorphisms in genes encoding toll-like receptors 7, 8 and 9 in Danish patients with systemic lupus erythematosus.

Molecular biology reports - 1 Sept 2014

Enevold C, Nielsen C H, Jacobsen R S, Hermansen M L F, Molbo D, Avlund K, Bendtzen K, Jacobsen S

Abstract excerpt

Several studies indicate a role for toll-like receptors (TLRs) in the pathogenesis of systemic lupus erythematosus (SLE). We aimed to investigate the risk of SLE and typical clinical and serological manifestations of SLE potentially conferred by selected single nucleotide polymorphisms (SNPs) of genes encoding TLR7, TLR8, and TLR9. Using a multiplexed bead-based assay, we analyzed eight SNPs in a cohort of 142...

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Identifiers

PMID: 24919757
DOI: 10.1007/s11033-014-3447-4

Genes

TLR7
TLR8
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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