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Article

Investigation of TLR5 and TLR7 as candidate genes for susceptibility to systemic lupus erythematosus.

Clinical and experimental rheumatology - 1 Jan 2000

Sánchez E, Callejas-Rubio J L, Sabio J M, Gónzalez-Gay M A, Jimenez-Alonso J, Micó L, de Ramón E, Camps M, Suarez A, Gutierrez C, Garcia-Portales R, Tolosa C, Ortego-Centeno N, Sánchez-Román J, Garcia-Hernández F J, Gónzalez-Escribano M F, Martin J

Abstract excerpt

OBJECTIVES: The aim of this study was to evaluate the relevance of genetic variants of TLR5 (rs5744168) and TLR7 (rs179008) gene in systemic lupus erythematosus (SLE) in a Spanish population. MATERIAL AND METHODS: Our study population consisted of 752 SLE patients and 1107 healthy controls. All individual were of Spanish Caucasian origin. The TLR5 and TLR7 polymorphisms were genotyped using a PCR system with...

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Source

Identifiers

PMID: 19473567

Genes

TLR5
TLR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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