Article
Toll-like receptor 7 gene single nucleotide polymorphisms and the risk for systemic lupus erythematosus: a case-control study.
Zeitschrift fur Rheumatologie - 1 Jun 2018
Raafat I I, El Guindy N, Shahin R M H, Samy L A, El Refai R M
Abstract excerpt
BACKGROUND: Toll-like receptors (TLRs) are a family of pattern-recognition receptors which play a role in eliciting innate/adaptive immune responses and developing chronic inflammation. So, the aim of this study was to analyze the effect of TLR7 gene single nucleotide polymorphisms (SNPs) rs3853839 and rs179019 on systemic lupus erythematosus (SLE) susceptibility and to assess their relations with various...
Topics
- Adult
- Case-Control Studies
- Egypt
- Female
- Genetic Predisposition to Disease
- Humans