Article
ITGAM is a risk factor to systemic lupus erythematosus and possibly a protection factor to rheumatoid arthritis in patients from Mexico.
PloS one - 1 Jan 2019
Ramírez-Bello Julian, Sun Celi, Valencia-Pacheco Guillermo, Singh Bhupinder, Barbosa-Cobos Rosa Elda, Saavedra Miguel A, López-Villanueva Ricardo F, Nath Swapan K
Abstract excerpt
INTRODUCTION: ITGAM has consistently been associated with susceptibility to systemic lupus erythematosus (SLE) in many ethnically diverse populations. However, in populations with higher Amerindian ancestry (like Yucatan) or highly admixed population (like Mexican), ITGAM has seldom been evaluated (except few studies where patients with childhood-onset SLE were included). In addition, ITGAM has seldom been...
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