Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IRF5 Variants Are Risk Factors for Systemic Lupus Erythematosus in Two Mexican Populations.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases - 1 Oct 2024

López-Briceño Isaac A, Ramírez-Bello Julian, Montúfar-Robles Isela, Barbosa-Cobos Rosa Elda, Ángulo-Ramírez Angélica V, Valencia-Pacheco Guillermo

Abstract excerpt

INTRODUCTION: Interferon regulatory factor 5 ( IRF5 ) is one of the pivotal genes implicated in systemic lupus erythematosus (SLE) among diverse ethnic groups, including Europeans, Asians, Hispanics, and Africans. Notably, its significance appears particularly pronounced among Hispanic populations. Previous studies have identified several single-nucleotide variants within IRF5 , such as rs2004640G/T,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Interferon Regulatory Factors

Share to Lupus Erythematosus, Systemic

Share to Mexico

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Identifiers

PMID: 39271190
DOI: 10.1097/RHU.0000000000002121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IRF5 Variants Are Risk Factors for Systemic Lupus Erythematosus in Two Mexican Populations.PMID 39271190Read ↗

Variants in the interferon regulatory factor 5 gene confer genetic risk for systemic lupus erythematosus in a Han Chinese population.Semantic proximity Read ↗

Association of the polymorphisms rs179008 (TLR7), rs2004640 (IRF5), rs1800795 (IL-6) and rs2280788 (CCL5) with systemic lupus erythematosus in women of Mayan ethnicity from Yucatan.Semantic proximity Read ↗

A meta-analysis of the association of IRF5 polymorphism with systemic lupus erythematosus.Semantic proximity Read ↗

Genetic association of IRF5 with SLE in Mexicans: higher frequency of the risk haplotype and its homozygozity than Europeans.Semantic proximity Read ↗

Interferon regulatory factor-5 is genetically associated with systemic lupus erythematosus in African Americans.Semantic proximity Read ↗

Association of the IRF5 rs2070197 polymorphism with systemic lupus erythematosus: a meta-analysis.Semantic proximity Read ↗

Variants in IRF5 Increase the Risk of Primary Sjögren's Syndrome in the Mexican Population.Semantic proximity Read ↗

Different genetic effects of interferon regulatory factor 5 (IRF5) polymorphisms on systemic lupus erythematosus in a Korean population.Semantic proximity Read ↗

Association of a common interferon regulatory factor 5 (IRF5) variant with increased risk of systemic lupus erythematosus (SLE).Semantic proximity Read ↗

Interferon regulatory factor 5 gene polymorphism in Egyptian children with systemic lupus erythematosus.Semantic proximity Read ↗

Genetic polymorphisms in genes involved in the type I interferon system (STAT4 and IRF5): association with Asian SLE patients.Semantic proximity Read ↗

Genetics research in systemic lupus erythematosus for clinicians: methodology, progress, and controversies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.