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Article

Association of TLR7 copy number variation with susceptibility to childhood-onset systemic lupus erythematosus in Mexican population.

Annals of the rheumatic diseases - 1 Oct 2010

García-Ortiz Humberto, Velázquez-Cruz Rafael, Espinosa-Rosales Francisco, Jiménez-Morales Silvia, Baca Vicente, Orozco Lorena

Abstract excerpt

OBJECTIVE: Variations in gene copy number (CNV) have been recognised as a hereditable source of susceptibility in human complex diseases. Recent studies have shown that Tlr7 gene dosage has a significant contribution in the autoimmune-enhancing effect in mouse models of systemic lupus erythematos...

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Source

Identifiers

PMID: 20525845
DOI: 10.1136/ard.2009.124313

Genes

TLR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20525845-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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