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Article

Impact of CYBA genotypes on severity and progression of multiple sclerosis.

European journal of neurology - 1 May 2022

Törnell Andreas, Kiffin Roberta, Haghighi Sara, Mossberg Natalia, Andersen Oluf, Hellstrand Kristoffer, Martner Anna

Abstract excerpt

BACKGROUND AND PURPOSE: The NOX2 enzyme of myeloid cells generates reactive oxygen species (ROS) that have been implicated in the pathology of multiple sclerosis (MS). We aimed to determine the impact of genetic variation within CYBA, which encodes the functional CYBA/p22phox subunit of NOX2, on MS severity and progression. METHODS: One hundred three MS patients with up to 49 (median = 17) years follow-up time...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multiple Sclerosis, Chronic Progressive

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Source

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Identifiers

PMID: 35073438
DOI: 10.1111/ene.15259
PMCID: PMC9303184

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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