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Article

Variation of genes encoding nitric oxide synthases and antioxidant enzymes as potential risks of multiple sclerosis development: a preliminary study.

Scientific reports - 22 Jun 2022

Wigner Paulina, Dziedzic Angela, Synowiec Ewelina, Miller Elzbieta, Bijak Michal, Saluk-Bijak Joanna

Abstract excerpt

Multiple sclerosis (MS) is a neurodegenerative disease characterized by a variable clinical course and diverse pathophysiology, including nitrative and oxidative stresses as well as inflammation. We aimed to detect the potential association between five selected single-nucleotide polymorphisms (SNPs) in genes encoding nitric oxide synthetases as well as antioxidant enzymes and the development of MS in a Polish...

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Identifiers

PMID: 35732787
DOI: 10.1038/s41598-022-14795-6
PMCID: PMC9217808

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