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Article

Allelic variations in the CYBA gene of NADPH oxidase and risk of kidney complications in patients with type 1 diabetes.

Free radical biology & medicine - 1 Sept 2015

Patente Thiago A, Mohammedi Kamel, Bellili-Muñoz Naïma, Driss Fathi, Sanchez Manuel, Fumeron Frédéric, Roussel Ronan, Hadjadj Samy, Corrêa-Giannella Maria Lúcia, Marre Michel, Velho Gilberto

Abstract excerpt

Oxidative stress plays a pivotal role in the pathophysiology of diabetic nephropathy, and the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase system is an important source of reactive oxygen species in hyperglycemic conditions in the kidney. Plasma concentration of advanced oxidation protein products (AOPP), a marker of oxidative stress, is increased in patients with diabetic nephropathy. We...

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Share to Diabetes Mellitus, Type 1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Kidney Failure, Chronic

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Source

Identifiers

PMID: 25862415
DOI: 10.1016/j.freeradbiomed.2015.04.002

Genes

CYBA
MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Allelic variations in the CYBA gene of NADPH oxidase and risk of kidney complications in patients with type 1 diabetes.PMID 25862415Read ↗

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