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Article

Three common polymorphisms in the CYBA gene form a haplotype associated with decreased ROS generation.

Human mutation - 1 Jul 2009

Bedard Karen, Attar Homa, Bonnefont Jérôme, Jaquet Vincent, Borel Christelle, Plastre Olivier, Stasia Marie-José, Antonarakis Stylianos E, Krause Karl-Heinz

Abstract excerpt

NOX enzymes are reactive oxygen species (ROS)-generating NADPH oxidases. Several members of the NOX family depend on the p22(phox) subunit, encoded by the CYBA gene. CYBA is highly polymorphic, and has been widely studied as a potential risk factor for various diseases, with conflicting results. In the present study, we used Epstein-Barr (EBV)-transformed B-lymphocytes from 50 healthy unrelated individuals to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19388116
DOI: 10.1002/humu.21029

Genes

CYBA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Three common polymorphisms in the CYBA gene form a haplotype associated with decreased ROS generation.PMID 19388116Read ↗

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