No evidence for association between rs10191329 severity locus and longitudinal disease severity in 1813 relapse-onset multiple sclerosis patients from the MSBase registry.

doi:10.1177/13524585241240406

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No evidence for association between rs10191329 severity locus and longitudinal disease severity in 1813 relapse-onset multiple sclerosis patients from the MSBase registry.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Aug 2024

Campagna Maria Pia, Havrdova Eva Kubala, Horakova Dana, Izquierdo Guillermo, Matesanz Fuencisla, Eichau Sara, Lechner-Scott Jeannette, Taylor Bruce V, García-Sanchéz Maria-Isabel, Alcina Antonio, van der Walt Anneke, Butzkueven Helmut, Jokubaitis Vilija G

Abstract excerpt

BACKGROUND: The International Multiple Sclerosis Genetics Consortium and MultipleMS Consortium recently reported a genetic variant associated with multiple sclerosis (MS) severity. However, it remains unclear if these variants remain associated with more robust, longitudinal measures of disease severity. METHODS: We examined the top variant, rs10191329, from Harroud et al.'s study in 1813 relapse-onset MS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38511853
DOI: 10.1177/13524585241240406
PMCID: PMC11363458

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