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Article

Association of NOX2 subunits genetic variants with autoimmune diseases.

Free radical biology & medicine - 1 Sept 2018

Zhong Jianghong, Olsson Lina M, Urbonaviciute Vilma, Yang Min, Bäckdahl Liselotte, Holmdahl Rikard

Abstract excerpt

A single nucleotide polymorphism in Ncf1 has been found with a major effect on chronic inflammatory autoimmune diseases in the rat with the surprising observation that a lower reactive oxygen response led to more severe diseases. This finding was subsequently reproduced in the mouse and the effect operates in many different murine diseases through different pathogenic pathways; like models for rheumatoid...

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Source

Identifiers

PMID: 29526808
DOI: 10.1016/j.freeradbiomed.2018.03.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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