Article
Association of CYBB polymorphisms with tuberculosis susceptibility in the Chinese Han population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2015
Liu Qianqian, Wang Jing, Sandford Andrew J, Wu Jingcan, Wang Yu, Wu Shouquan, Ji Guiyi, Chen Guo, Feng Yulin, Tao Chuanmin, He Jian-Qing
Abstract excerpt
OBJECTIVE: Reactive oxygen species (ROS) play a major role in the nonspecific innate immune response to invading microorganisms, such as Mycobacterium tuberculosis (MTB). Gp91phox, encoded by CYBB, serves as a key functional subunit of the Nicotinamide Adenine Dinucleotide Phosphate (NADPH) oxida...
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