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Article

Association of CYBB polymorphisms with tuberculosis susceptibility in the Chinese Han population.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2015

Liu Qianqian, Wang Jing, Sandford Andrew J, Wu Jingcan, Wang Yu, Wu Shouquan, Ji Guiyi, Chen Guo, Feng Yulin, Tao Chuanmin, He Jian-Qing

Abstract excerpt

OBJECTIVE: Reactive oxygen species (ROS) play a major role in the nonspecific innate immune response to invading microorganisms, such as Mycobacterium tuberculosis (MTB). Gp91phox, encoded by CYBB, serves as a key functional subunit of the Nicotinamide Adenine Dinucleotide Phosphate (NADPH) oxidase complex, which is pivotal to ROS generation. Therefore, the aim of the study was to investigate the association of...

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Identifiers

PMID: 25929165
DOI: 10.1016/j.meegid.2015.04.026

Genes

CYBB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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