Article
Association between SNPs of Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), programmed cell death 1 (PD-1)and the susceptibility to chronic Hepatitis C infection in virus C-infected patients.
Virus research - 1 Mar 2022
Ali El Shaimaa Gomaa, Bassyouni Rasha H, Abdelaleem Omayma O, Hassan Essam A, Gaber Sylvana N
Abstract excerpt
BACKGROUND: Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death 1 (PD-1) are immune inhibitory factors that provide inhibitory signals to T cells. METHODS: A case-controlled genetic association study was conducted in478 patients (160 patients with chronic Hepatitis C virus (HCV) and diabetes mellitus (DM) and156 patients with chronic HCV without DM) and162healthy controls. We genotyped...
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