Article
Association between hepatitis B viral burden in chronic infection and a functional single nucleotide polymorphism of the PDCD1 gene.
Journal of clinical immunology - 1 Nov 2010
Zheng Linghua, Li Dongling, Wang Fusheng, Wu Hao, Li Xiaozhu, Fu Junliang, Chen Xinyue, Wang Lizhong, Liu Yang, Wang Shengdian
Abstract excerpt
BACKGROUND: PD-1, encoded by PDCD1, is highly expressed on virus-specific T cells and plays critical roles in modulating anti-virus immune responses in chronic viral infection. It is unknown, however, whether polymorphisms of the PDCD1 are associated with viral clearance during chronic viral infections. METHODOLOGY AND PRINCIPAL FINDINGS: Here, we used the polymerase chain reaction-restriction fragment length...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.