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Article

Association of toll‐like receptor 4 polymorphisms with type 2 diabetes mellitus

20 Nov 2012

Abstract excerpt

Toll-like receptor 4 (TLR4) plays important roles in modulating innate immunity. Type 2 diabetes mellitus (T2DM) is a chronic and complex disease that is characterized by impaired insulin resistance and dysregulated immune response. In the current study, we investigated whether TLR4 polymorphisms were correlated with susceptibility to T2DM in the Chinese population. Four TLR4 polymorphisms (-2431T/C, Asp299Gly,...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 23163570
DOI: 10.1111/apm.12027

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