Article
An association study of functional polymorphic genes IRF-1, IFNGR-1, and IFN-γ with disease progression, aspartate aminotransferase, alanine aminotransferase, and viral load in chronic hepatitis B and C.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Jan 2013
Korachi May, Ceran Nurgül, Adaleti Riza, Nigdelioglu Adil, Sökmen Mehmet
Abstract excerpt
BACKGROUND: Investigational approaches based on genome-wide association studies have proven useful in identifying genetic predictors for many diseases, including susceptibility to chronic hepatitis B and C. In these studies, the majority of genetic variants that have shown a positive association have been identified in genes involved in the immune response. In this study IFN-γ, IFNGR-1, and IRF-1 genes were...
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