Article
Genetic variations in humans associated with differences in the course of hepatitis C.
Biochemical and biophysical research communications - 30 Apr 2004
Saito Takafumi, Ji Guijin, Shinzawa Haruhide, Okumoto Kazuo, Hattori Etsuko, Adachi Tohru, Takeda Tadashi, Sugahara Kazuhiko, Ito Jun-itsu, Watanabe Hisayoshi, Saito Koji, Togashi Hitoshi, Ishii Keisuke, Matsuura Tadashi, Inageda Kiyoshi, Muramatsu Masaaki, Kawata Sumio
Abstract excerpt
The outcome of hepatitis C virus (HCV) infection varies among individuals, but the genetic factors involved remain unknown. We conducted a population-based association study in which 238 Japanese individuals positive for anti-HCV antibody were genotyped for 269 single nucleotide polymorphisms (SNPs) in 103 candidate genes that might influence the course of infection. Altogether, 50 SNPs in 32 genes were listed....
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