A Programmed Cell Death-1 Haplotype is Associated with Clearance of Hepatitis B Virus.

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Article

A Programmed Cell Death-1 Haplotype is Associated with Clearance of Hepatitis B Virus.

Annals of clinical and laboratory science - 1 May 2017

Hou Zhouhua, Zhou Qing, Lu Menghou, Tan Deming, Xu Xuwen

Abstract excerpt

PURPOSE: Programmed cell death 1 (PD-1) is an important immune checkpoint of T cells response and plays a critical role in chronic hepatitis B virus (HBV) infection. The purpose of this study was to investigate the associations between PD-1 polymorphisms and susceptibility and disease progression of chronic HBV infection. METHODS: In this case-control study, 299 cases with chronic HBV infection comprised of 99...

Topics

Adult
Asian People
Case-Control Studies
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Haplotypes
Hepatitis B, Chronic
Humans
Linkage Disequilibrium
Male
Middle Aged
Phylogeny
Polymorphism, Single Nucleotide
Programmed Cell Death 1 Receptor

Source

Open in PubMed

Identifiers

PMID: 28667037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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