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Article

Homologous recombination DNA repair gene RAD51, XRCC2 & XRCC3 polymorphisms and breast cancer risk in South Indian women.

PloS one - 1 Jan 2000

Rajagopal Taruna, Seshachalam Arun, Rathnam Krishna Kumar, Talluri Srikanth, Venkatabalasubramanian Sivaramakrishnan, Dunna Nageswara Rao

Abstract excerpt

BACKGROUND: Homologous recombination repair (HRR) accurately repairs the DNA double-strand breaks (DSBs) and is crucial for genome stability. Genetic polymorphisms in crucial HRR pathway genes might affect genome stability and promote tumorigenesis. Up to our knowledge, the present study is the first to investigate the impact of HRR gene polymorphisms on BC development in South Indian women. The present...

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Identifiers

PMID: 35061678
DOI: 10.1371/journal.pone.0259761
PMCID: PMC8782413

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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