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Association of RAD51, XRCC1, XRCC2, and XRCC3 Polymorphisms with Risk of Breast Cancer.

Genetic testing and molecular biomarkers - 1 Jul 2023

Gupta Priyanka, Sambyal Vasudha, Guleria Kamlesh, Uppal Manjit Singh, Sudan Meena

Abstract excerpt

Background: DNA repair genes are among the low-penetrance genes implicated in breast cancer. However variants of DNA repair genes may alter their protein function thus leading to carcinogenesis. Breast cancer is the most common cancer among women in India. The aim of the present study was to identify association, if any, of single nucleotide polymorphisms (SNP's) in four genes involved in DNA repair pathways...

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PMID: 37522793
DOI: 10.1089/gtmb.2023.0012

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