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Article

Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241Met) polymorphisms with the risk of breast cancer: a case-control study in Egypt.

Genetic testing and molecular biomarkers - 1 Nov 2014

Ramadan Ragaa A, Desouky Lubna M, Elnaggar Mostafa A, Moaaz Mai, Elsherif Amr M

Abstract excerpt

UNLABELLED: Various DNA damage, induced by endogenous and exogenous factors, is handled through DNA repair pathways such as X-ray repair cross-complementing protein (XRCC). Genetic variations in these pathways may have a joint or additive effect on various types of cancer, including the risk of breast cancer (BC). AIM: To evaluate the association of three single-nucleotide polymorphisms (SNPs) Arg399Gln,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25340946
DOI: 10.1089/gtmb.2014.0191

Genes

XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241Met) polymorphisms with the risk of breast cancer: a case-control study in Egypt.PMID 25340946Read ↗

Impact of XRCC1 genetic variants on its tissue expression and breast cancer risk: A case-control study.Semantic proximity Read ↗

XRCC1 Arg399Gln, Arg194Trp and Arg280His polymorphisms in breast cancer risk: a meta-analysis.Semantic proximity Read ↗

XRCC1 Arg399Gln gene polymorphism and breast cancer risk: a meta-analysis based on case-control studies.Semantic proximity Read ↗

Association of XRCC1 gene polymorphisms with breast cancer susceptibility in Saudi patients.Semantic proximity Read ↗

X-ray repair cross-complementing protein 1 and 3 polymorphisms and susceptibility of breast cancer in a Jordanian population.Semantic proximity Read ↗

Assessment of the Link between XRCC1 Arg399Gln Polymorphism and Breast Cancer: a Meta-Analysis in a Single Ethnic Group.Semantic proximity Read ↗

Investigation on XRCC1 genetic polymorphism and its relationship with breast cancer risk factors in Chinese women.Semantic proximity Read ↗

XRCC1 Arg399Gln polymorphism confers risk of breast cancer in American population: a meta-analysis of 10846 cases and 11723 controls.Semantic proximity Read ↗

DNA Repair Mechanism Gene, XRCC1A ( Arg194Trp) but not XRCC3 ( Thr241Met) Polymorphism Increased the Risk of Breast Cancer in Premenopausal Females: A Case-Control Study in Northeastern Region of India.Semantic proximity Read ↗

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Impact of DNA repair genes polymorphism (XPD and XRCC1) on the risk of breast cancer in Egyptian female patients.Semantic proximity Read ↗

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