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Evaluation of miRNA-binding-site SNPs of MRE11A, NBS1, RAD51 and RAD52 involved in HRR pathway genes and risk of breast cancer in China.

Molecular genetics and genomics : MGG - 1 Jun 2015

Wu Zhenzhen, Wang Peng, Song Chunhua, Wang Kaijuan, Yan Rui, Li Jingruo, Dai Liping

Abstract excerpt

MiRNA-binding-site single nucleotide polymorphisms (SNPs) in homologous recombination repair (HRR) pathway genes may change DNA repair capacity and affect susceptibility to cancer though complex gene-gene and gene-reproductive factors interactions. However, these SNPs associated with breast cancer (BC) are still unclear in Chinese women. Therefore, we conducted a case-control study to evaluate the genetic...

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Cell Cycle Proteins
MicroRNAs
MRE11 Homologue Protein
Nuclear Proteins
Rad51 Recombinase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rad52 DNA Repair and Recombination Protein

Recombinational DNA Repair

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Identifiers

PMID: 25566853
DOI: 10.1007/s00438-014-0983-5

Genes

RAD51
RAD52

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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