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Article

Polymorphisms in DNA Repair Gene XRCC3 and Susceptibility to Breast Cancer in Saudi Females.

BioMed research international - 1 Jan 2016

Ali Alaa Mohammed, AbdulKareem Huda, Al Anazi Mohammad, Reddy Parine Narasimha, Shaik Jilani Purusottapatnam, Alamri Abdullah, Ali Khan Pathan Akbar, Warsy Arjumand

Abstract excerpt

We investigated three common polymorphisms (SNPs) in the XRCC3 gene (rs861539, rs1799794, and rs1799796) in 143 Saudi females suffering from breast cancer (median age = 51.4 years) and 145 age matched normal healthy controls. DNA was extracted from whole blood and genotyping was conducted using PCR-RFLP. rs1799794 showed significant association, where AA and AA+AG occurred at a significantly higher frequency in...

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Source

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Identifiers

PMID: 26881229
DOI: 10.1155/2016/8721052
PMCID: PMC4736606

Genes

XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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