Article
DNA repair genes hOGG1, XRCC1 and ERCC2 polymorphisms and their molecular mapping in breast cancer patients from India.
Molecular biology reports - 1 Jul 2020
Rajagopal Taruna, Seshachalam Arun, Rathnam Krishna Kumar, Jothi Arunachalam, Viswanathan Swarna, Talluri Srikanth, Dunna Nageswara Rao
Abstract excerpt
Identification of modifier genes predisposing to breast cancer (BC) phenotype remains a significant challenge and varies with ethnicity. The genetic variability observed in DNA repair genes may modulate the cell's ability to repair the damaged DNA and hence, evaluation of genetic variants in crucial DNA damage repair genes is of clinical importance. We performed the present study to evaluate the role of...
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