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Phenome-wide association study of the major histocompatibility complex region in the Korean population identifies novel association signals.

Human molecular genetics - 17 Aug 2022

Kim Chanwoo, Kim Young Jin, Choi Wanson, Jang Hye-Mi, Hwang Mi Yeong, Jung Sunwoo, Lim Hyunjoon, Hong Sang Bin, Yoon Kyungheon, Kim Bong-Jo, Park Hyun-Young, Han Buhm

Abstract excerpt

Human leukocyte antigen (HLA) gene variants in the major histocompatibility complex (MHC) region are associated with numerous complex human diseases and quantitative traits. Previous phenome-wide association studies (PheWAS) for this region demonstrated that HLA association patterns to the phenome have both population-specific and population-shared components. We performed MHC PheWAS in the Korean population by...

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PMID: 35043955
DOI: 10.1093/hmg/ddac016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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