Article
Association between C-281A and val66met functional polymorphisms of BDNF gene and risk of recurrent major depressive disorder in Polish population.
Journal of molecular neuroscience : MN - 1 Mar 2011
Suchanek Renata, Owczarek Aleksander, Kowalczyk Małgorzata, Kucia Krzysztof, Kowalski Jan
Abstract excerpt
According to neurotrophic hypothesis, brain-derived neurotrophic factor (BDNF) is the potential candidate involved in the pathogenesis of depression. We examined the influence of C-281A (rs28383487) and val66met (rs6265) functional polymorphisms in BDNF gene on vulnerability to major depressive disorder, recurrent (MDD-R), in a Caucasian population. To our knowledge, this is the first case-control study to...
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