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Article

Unipolar depression and hippocampal volume: impact of DNA sequence variants of the glucocorticoid receptor gene.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2008

Zobel Astrid, Jessen Frank, von Widdern Olrik, Schuhmacher Anna, Höfels Susanne, Metten Martin, Rietschel Marcella, Scheef Lukas, Block Wolfgang, Becker Tim, Schild Hans H, Maier Wolfgang, Schwab Sibylle G

Abstract excerpt

Glucocorticoid receptor (GR) plays a major role in regulation of the hypothalamic-pituitary-adrenocortical (HPA) system; HPA dysregulation represents the most consistent biological pattern of depression. Multiple functional polymorphisms are known for the GR gene, which might influence the develo...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18286599
DOI: 10.1002/ajmg.b.30709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18286599-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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