Article
Identification of putative genetic variants in major depressive disorder patients in Pakistan.
Molecular biology reports - 1 Mar 2022
Qazi Sarah Rizwan, Irfan Muhammad, Ramzan Zoobia, Jahanzaib Muhammad, Khan Maleeha Zaman, Nasir Mahrukh, Shakeel Muhammad, Khan Ishtiaq Ahmad
Abstract excerpt
BACKGROUND: Major depressive disorder (MDD) is a polygenic, and highly prevalent disorder affecting 322 million people globally. It results in several psychological changes which adversely affect different dimensions of life and may lead to suicide. METHODS: Whole exome sequencing of 15 MDD patients, enrolled at the Dr. A. Q. Khan Institute of Behavioral Sciences, Karachi, was performed using NextSeq500....
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