Article
TRAPing Ghrelin-Activated Circuits: A Novel Tool to Identify, Target and Control Hormone-Responsive Populations in TRAP2 Mice.
International journal of molecular sciences - 5 Jan 2022
Stoltenborg Iris, Peris-Sampedro Fiona, Schéle Erik, Le May Marie V, Adan Roger A H, Dickson Suzanne L
Abstract excerpt
The availability of Cre-based mouse lines for visualizing and targeting populations of hormone-sensitive cells has helped identify the neural circuitry driving hormone effects. However, these mice have limitations and may not even be available. For instance, the development of the first ghrelin receptor (Ghsr)-IRES-Cre model paved the way for using the Cre-lox system to identify and selectively manipulate...
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