Article
Ghrelin receptor signaling targets segregated clusters of neurons within the nucleus of the solitary tract.
Brain structure & function - 1 Sept 2018
Cornejo María Paula, De Francesco Pablo Nicolás, García Romero Guadalupe, Portiansky Enrique L, Zigman Jeffrey M, Reynaldo Mirta, Perello Mario
Abstract excerpt
Ghrelin is a stomach-derived hormone that regulates a variety of biological functions such as food intake, gastrointestinal function and blood glucose metabolism, among others. Ghrelin acts via the growth hormone secretagogue receptor (GHSR), a G-protein-coupled receptor located in key brain areas that mediate specific actions of the hormone. GHSR is highly expressed in the nucleus of the solitary tract (NTS),...
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