Article

Discrete TrkB-expressing neurons of the dorsomedial hypothalamus regulate feeding and thermogenesis

2020-09-04

Abstract excerpt

Mutations in the TrkB neurotrophin receptor lead to profound obesity in humans, and expression of TrkB in the dorsomedial hypothalamus (DMH) is critical for maintaining energy homeostasis. However, the functional implications of TrkB-expressing neurons in the DMH (DMH TrkB ) on energy expenditure are unclear. Additionally, the neurocircuitry underlying the effect of DMH TrkB neurons on energy homeostasis has not...

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Literature Corpus work: a10f09e8-9761-5349-9f3c-cd1457a4c9f2
DOI: 10.1101/2020.09.02.279745

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