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Article

The role of heme oxygenase-1 promoter polymorphisms in human disease.

Free radical biology & medicine - 15 Oct 2004

Exner Markus, Minar Erich, Wagner Oswald, Schillinger Martin

Abstract excerpt

Heme oxygenase (HO) seems to be a novel protective factor with potent anti-inflammatory, anti-oxidant, and anti-proliferative effects. HO-1, the inducible isoform, is expressed in various tissues and is upregulated by multiple stimuli. However, humans differ quantitatively in their ability to mount an HO-1 response, modulated by two potentially functional polymorphisms in the HO-1 gene promoter region. From...

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Identifiers

PMID: 15451051
DOI: 10.1016/j.freeradbiomed.2004.07.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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