Article
Association between heme oxygenase-1 gene promoter polymorphisms and metabolic syndrome in Iranians.
Molecular biology reports - 1 Mar 2012
Javanmard Shaghayegh Haghjooy, Keyhanian Kiandokht, Loghmani Parisa, Samety Amir Abbas, Haghdoost Faraidoon, Rafiei Laleh, Talaei Mohammad, Asgari Sedigheh, Jazi Mohammad Hashemi, Sarrafzadegan Nizal
Abstract excerpt
Heme oxygenase-1 (HO-1) which is a rate-limiting enzyme in heme degradation processes shows a dinucleotide GT repeat in the promoter that alters the level of gene transcription. This study is aimed to assess the association of HO-1 gene promoter polymorphism and metabolic syndrome (MetS). A hundred and fifty two individuals, who were followed in Isfahan Cohort Study since 2001, were enrolled in this study. They...
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