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Article

The heme oxygenase-1 genotype is a risk factor to renal impairment of IgA nephropathy at diagnosis, which is a strong predictor of mortality.

Journal of Korean medical science - 1 Jan 2009

Chin Ho Jun, Cho Hyun Jin, Lee Tae Woo, Na Ki Young, Yoon Hyung Jin, Chae Dong-Wan, Kim Suhnggwon, Jeon Un Sil, Do Jun-Young, Park Jong-Won, Yoon Kyung-Woo, Shin Young-Tai, Lee Kang Wook, Na Ki-Ryang, Cha Dae Ryong, Kang Young Sun

Abstract excerpt

The induction of heme oxygenase-1 (HO-1) ameliorates oxidative stress and inflammatory process, which play important roles in IgA nephropathy. We hypothesized length polymorphism in the promoter region of the HO-1 gene, which is related to the level of gene transcription, is associated with disease severity of IgA nephropathy. The subjects comprised 916 patients with IgA nephropathy and gene data. Renal...

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Share to Disease Progression
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerular Filtration Rate

Share to Glomerulonephritis, IGA

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Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 19194559
DOI: 10.3346/jkms.2009.24.S1.S30
PMCID: PMC2633190

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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