Article
A promoter variant of the heme oxygenase-1 gene may reduce the incidence of ischemic heart disease in Japanese.
Atherosclerosis - 1 Apr 2004
Ono Koh, Goto Yoichi, Takagi Shuichi, Baba Shunroku, Tago Naomi, Nonogi Hiroshi, Iwai Naoharu
Abstract excerpt
Heme oxygenase-1 (HO-1) has been suggested to have antiatherogenic properties. This study was designed to examine the relationship between the HO-1 gene (HMOX1) and ischemic heart disease. The study population consisted of 1972 control subjects and 597 subjects with ischemic heart disease (myocardial infarction (MI) n = 393, HMOX1 n = 204). The control subjects were consecutively selected from the Suita study, an...
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