Article
Association Between Heme Oxygenase-1 Promoter Polymorphisms and the Development of Albuminuria in Type 2 Diabetes: A Case-Control Study.
Medicine - 1 Oct 2015
Lee Eun Young, Lee Yong-Ho, Kim Soo Hyun, Jung Kyu Sik, Kwon Obin, Kim Beom Seok, Nam Chung Mo, Park Chun Sik, Lee Byung-Wan, Kang Eun Seok, Cha Bong-Soo, Lee Hyun Chul
Abstract excerpt
Heme oxygenase (HO)-1 is a key enzyme in cytoprotective mechanisms against oxidative stress in the cardiovascular-renal system. The T(-413)A single nucleotide polymorphism (SNP) and (GT)n microsatellite polymorphism in the HO-1 gene promoter modulate the HO-1 gene transcriptional activity and these polymorphisms are associated with various human diseases.We investigated the association between HO-1 promoter...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
