Article
Genotype and allele frequencies of heme oxygenase-1 promoter region in a Greek cohort.
Chinese medical journal - 1 Oct 2011
Katana Eleni P, Skoura Lemonia G, Scouras Zacharias G, Daniilidis Michail A
Abstract excerpt
BACKGROUND: Heme oxygenase-1 (HO-1) is an enzyme, which catabolizes heme into carbon monoxide, biliverdin and free iron. The induction of this enzyme is an important cytoprotective mechanism, which occurs as an adaptive and beneficial response to a wide variety of oxidant stimuli. HO-1 inducibility is mainly modulated by a (GT)(n) polymorphism in the promoter region, and has been shown that short (S) repeats are...
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