Article
Association between heme oxygenase-1 gene promoter polymorphisms and type 2 diabetes in a Chinese population.
American journal of epidemiology - 15 Sept 2009
Song Fangfang, Li Xiangyang, Zhang Muxun, Yao Ping, Yang Nianhong, Sun Xiufa, Hu Frank B, Liu Liegang
Abstract excerpt
The authors aimed to determine whether 2 functional polymorphisms in the heme oxygenase-1 (HO-1) gene promoter are associated with type 2 diabetes mellitus (T2DM). A Chinese case-control study involving 1,103 newly diagnosed T2DM patients, 371 patients with impaired glucose regulation (IGR), and 1,615 controls was performed (December 2004-December 2007). A (GT)(n) microsatellite polymorphism and a single...
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