Article
A detection method for the capture of genomic signatures: From disease diagnosis to genome editing.
Methods in enzymology - 1 Jan 2021
Benamozig Orléna, Baudrier Lou, Billon Pierre
Abstract excerpt
Variations in the genetic information originate from errors during DNA replication, error-prone repair of DNA damages, or genome editing. The most common approach to detect changes in DNA sequences employs sequencing technologies. However, they remain expensive and time-consuming, limiting their utility for routine laboratory experiments. We recently developed DinucleoTidE Signature CapTure (DTECT). DTECT is a...
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