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Article

Pan-Cancer Analysis of Clinical Relevance via Telomere Maintenance Mechanism

14 Oct 2021

Abstract excerpt

Understanding the telomere maintenance mechanism (TMM) in immortal cancer cells is vital for TMM-targeted therapies in clinical settings. In this study, we classified four telomere maintenance mechanisms into telomerase, ALT, telomerase + ALT, and non-defined telomere maintenance mechanism (NDTMM) across 31 cancer types using 10,704 transcriptomic datasets from The Cancer Genome Atlas. Our results demonstrated...

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Share to Cancer Genomics and Diagnostics
Share to Epigenetics and DNA Methylation
Share to Telomeres, Telomerase, and Senescence

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PMID: 34681758
DOI: 10.3390/ijms222011101

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