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Article

ALT: A Multi-Faceted Phenomenon.

Genes - 27 Jan 2020

Sommer Aurore, Royle Nicola J

Abstract excerpt

One of the hallmarks of cancer cells is their indefinite replicative potential, made possible by the activation of a telomere maintenance mechanism (TMM). The majority of cancers reactivate the reverse transcriptase, telomerase, to maintain their telomere length but a minority (10% to 15%) utilize an alternative lengthening of telomeres (ALT) pathway. Here, we review the phenotypes and molecular markers specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32012790
DOI: 10.3390/genes11020133
PMCID: PMC7073516

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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ALT: A Multi-Faceted Phenomenon.PMID 32012790Read ↗

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