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Article

Pan-Cancer Analysis of Alternative Lengthening of Telomere Activity

7 Aug 2020

Abstract excerpt

Alternative lengthening of telomeres (ALT) is a telomerase-independent mechanism that extends telomeres in cancer cells. It influences tumorigenesis and patient survival. Despite the clinical significance of ALT in tumors, the manner in which ALT is activated and influences prognostic outcomes in distinct cancer types is unclear. In this work, we profiled distinct telomere maintenance mechanisms (TMMs) using 8953...

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Share to Epigenetics and DNA Methylation
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32784588
DOI: 10.3390/cancers12082207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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