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Telomere-related Markers for Cancer

6 Jan 2020

Abstract excerpt

Telomeres are structurally nucleoprotein complexes at termini of linear chromosomes and essential to chromosome stability/integrity. In normal human cells, telomere length erodes progressively with each round of cell divisions, which serves as an important barrier to uncontrolled proliferation and malignant transformation. In sharp contrast, telomere maintenance is a key feature of human malignant cells and...

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PMID: 31903880
DOI: 10.2174/1568026620666200106145340

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