Article

Telomere maintenance pathway activity analysis enables tissue- and gene-level inferences

2021-02-02

Abstract excerpt

<h4>ABSTRACT</h4> Telomere maintenance is one of the mechanisms ensuring indefinite divisions of cancer and stem cells. Good understanding of telomere maintenance mechanisms (TMM) is important for studying cancers and designing therapies. However, molecular factors triggering selective activation of either the telomerase dependent (TEL) or the alternative lengthening of telomeres (ALT) pathway are poorly understo...

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Literature Corpus work: 125bbdd4-35cf-517b-b6d7-4b310bcdfcaa
DOI: 10.1101/2021.02.01.429081

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